Leigh Syndrome Facts
1 in 40,000
individuals are affected by Leigh Syndrome
2 mo - 3 yrs
age when symptoms typically start, although earlier or later onset is also possible
Genetic mutations in nuclear DNA and mitochondrial DNA can cause this syndrome
If you or a family member has been diagnosed anywhere in the world with Leigh Syndrome, please enroll in the patient registry to make an important contribution to Leigh Syndrome research.
Support For Patients
You’re not alone in your journey. Navigate the challenges together, find hope, and build unstoppable strength with About Leigh Syndrome by your side.
History of Leigh Syndrome
Leigh syndrome is named after Dr. Denis Leigh, a neuropathologist in London, who first described the condition in 1951. It is characterized by specific brain lesions, which are a unique feature of the condition. These lesions typically appear in the basal ganglia, brainstem, and cerebellum. The affected areas often exhibit bilateral symmetrical necrotic or degenerative changes. These distinctive lesions are one of the key diagnostic markers used in identifying it.
Treatments and Trials
Treatments for Leigh syndrome are focused on keeping children comfortable and slowing disease progression. There is currently no FDA approved treatments or cure, although research and clinical trials are underway.